Having little ones comes with big questions. Whether you’re just starting your family planning or already pregnant, a carrier screen can help you understand your risk of passing on a genetic condition to your child.
The sooner you know your risks, the more you can do to plan for your family's future.
Ready to get started? Click the link in our bio.
Crohn's Disease, which is a chronic inflammatory disease of the intestinal tract, affects a diverse amount of people. Researchers have discovered that Crohn's Disease tends to run in families. In fact, the risk for developing IBD is between 1.5 percent and 28 percent for first-degree relatives of an affected person. While genetic background plays a clear role, environmental factors such as diet, smoking, lifestyle, pollutants, and others may impact onset, progression, and relapse of the disease.
Since the GFPD's founding, we have provided grants for medical research labs all over the world. Championing the scientific community to share their findings with each other is incredibly important for rare disease research to continue to move forward.
Any amount helps! Your support not only provides funds for lab time, but the space and platforms needed to collaborate about the best possible treatments for our #PBDWarriors .
Make a donation today or create your own fundraiser to raise even more funds: https://fb.com/fund/thegfpd/
A great example of eating the food your body and genes are designed for are lactose and gluten 🧬🥛🍪
Only 25% of the population has the gene that processes lactose after age 3.
Only a quarter of the population are genetically designed to regularly digest dairy!
For the rest of us, when we eat dairy, our bodies struggle to break it down.
For some it may become an allergy but for most, it becomes a slow, long term irritant in the body that we can’t break down or extract nutrients from.
Over time, this contributes to inflammation, weight gain, diabetes, and other forms of chronic disease.
Gluten presents a similar issue. Not all of us can break it down.
By the time it reaches our gut, it can cause damage to our gut lining and our immune systems.
Wouldn’t it be great to know if these types of foods cause you issues before it’s too late?
With DNA testing you can.
There's no need to guess, a simple cheek swab can tell you how you can best eat to support your genes.
Experience the adventure with our family’s legacy, grown in hand crafted soul and fueled by renewable energy. We are honored to flourish in an era where we can share the fruits of our endeavors.
1 1140 minutes ago
Genetics, immune dysfunction and chronic illness... Toxins also trigger inflammatory responses much like infectious agents. The immune system likes the nice balance of a bell curve. It prefers to be in the middle! If it struggles to clear an infection ,the burden may be too great to effectively deal with environmental exposures and other debris further compounding the scenario.
I'm often asked why some individuals exposed to illnesses are unaffected while others prove to suffer devastating symptoms sometimes long-term in nature.
Read more: somerdelsignore.com
1 240 minutes ago
I’ve been an artist for FOUR YEARS NOW! 🎨 👩🏼🎨 This drawing was on my one-year anniversary. What an incredible journey of self-discovery and creativity it has been. The path of being an artist has led me to incredible opportunities, and meeting people from all over the world who collect my art. I’ve taught workshops and gathered with women to create art. It has been the biggest source of inspiration I’ve had in the last several years. Thank you to all my collectors and collaborators, students and appreciators. And when I began, I certainly didn’t think it would evolve into erotic art. It’s such a freedom to declare that I am an artist! 🙏🏼❤️ .
After a lifetime of wishing I could draw but feeling no inspiration for what exactly it was I really wanted, finally decided I wanted to draw faces of beautiful women, so I set out to teach myself. My first girl I drew off the page, such was my sense of proportion, so I bought a couple of books and started learning. It hurt my brain literally to learn how to draw, but after one year, this is my progress! ✨ I am learning perception, shadows and light, what people actually look like, and so much more! It's been the greatest artistic learning experience for me to date. My grandfather was a famous naval artist in WWII, but it never really registered that it might be genetic, so I'm believing it now! I drew this freckled girl #offthepage as a #throwback to that day one year ago... 🎱 #klovelearnstodraw#selftaught#art#artist#charcoal#pencils#bw#mysketchbook#fashionart#freckles#freckled#freckledgirl#fashionillustrator#fashion#illustrator#genetics#fambam#allinthefamily#111916#today#fashionillustration#artistsoninstagram#klove#forsale#facetime#overtheshoulder #💋 #KristinaLloydArt
Today's featured student is Brad Weiler!
Brad is a Marine Biology and Ecology PhD student at the University of Miami, Rosenstiel School of Marine and Atmospheric Science. He studies coral (host)-microbe interactions and disease pathogen identification in Dr. Javier del Campo’s lab. Read more about Brad’s research in our blog, Reefbites! Link in Bio
Hi, Brad. Great to have you on our icrs.students page. Could you give us an elevator pitch of what your research/project is about?
Corals, like humans and other animals, have an immune system, a collection of microbes that interact in a positive, neutral, or negative way with the coral host. If an alien microbe is introduced or the microbial community (microbiome) dynamics shift from environmental stress, coral health can become compromised. Due to the molecular nature of this research and the complexity of the coral microbiome, there is significant difficulty in confidently identifying disease pathogens- leaving this over 40-year-old field still missing crucial information. Here, we aim to use modern molecular techniques along with conventional culturing techniques to target pathogens responsible for various coral diseases (such as the relatively recent coral disease, scleractinian coral tissue loss disease that is decimating the Florida Reef Tract and surrounding regions). By isolating pathogens and understanding their genetic and ecological information, this research can help management make informed decisions on coral reef mitigation and future conservation.
. #reef#reefs#corals#research#science#oceansciences#oceanography#ecology#geology#biology#chemistry#genetics#ocean#symbiosis#climate#photooftheday #nature#fieldwork
✨The secret behind 𝘮𝘦𝘵𝘢𝘣𝘰𝘭𝘪𝘴𝘮✨
🤷🏼♀️What the heck does this word even mean?! We hear it all the time in the biology and nutrition world, but 𝘸𝘩𝘺?
✨It's because all of the functions in our body revolve around it.💫
✨𝐌𝐞𝐭𝐚𝐛𝐨𝐥𝐢𝐬𝐦 is defined simply as the biochemical processes in the body, consisting of breaking down and building up compounds. The main thing we are referring to in nutrition is the 𝘣𝘳𝘦𝘢𝘬𝘪𝘯𝘨 𝘥𝘰𝘸𝘯 𝘰𝘧 𝘧𝘰𝘰𝘥 𝘵𝘰 𝘧𝘰𝘳𝘮 𝘦𝘯𝘦𝘳𝘨𝘺.
🙋🏼♀️Here is the simple version:
✅1) Eat food, get calories and nutrients to power your body.
✅2) Eat 𝘵𝘰𝘰 𝘭𝘪𝘵𝘵𝘭𝘦 food, you run out of energy.
✅3) Eat 𝘵𝘰𝘰 𝘮𝘶𝘤𝘩 food, you store energy in your body (adipose, or fat).
✨This simple concept, at its core, is most definitely true. The 𝐡𝐚𝐫𝐝 part, however, is that there are 𝘯𝘰 𝘴𝘦𝘵 𝘯𝘶𝘮𝘣𝘦𝘳𝘴 𝘰𝘳 𝘮𝘦𝘯𝘶𝘴 that can guarantee perfect health for every body. Every single one of us if different.
💫1. We are all born with different genetics. These genes predispose us to certain things. In the same way we are different heights, have different hair colors, and different blood types, we also have different food preferences, gain our weight (both fat and muscle) differently, and have different basal metabolic rates (BMR's).
💫2. We all maintain different lifestyles, and our lifestyles have an effect on our body's functions and metabolism. The types of food we eat, how much activity we engage in, our environments, etc., all have an effect on our metabolism. We can actually change (within genetic limits) our BMR!
✨So how do we do this? How do we know what is right for our own bodies?
✨Tune in tomorrow for the answer! 🤗
Today's BOGO is Buy one get TWO Free
Buy Digestzen which is a blend of Anise seed, Peppermint, Ginger, Caraway seed, Coriander, Tarragon, and Fennel and get Tamer and Stronger free from the doTERRA kids kit for free!🎇
Digestzen is an absolute must have if you EVER have any kind of stomach upset from bloating to being carsick and everything in between. I carry this with my at all times because my stomach is a absolute mess most of the time.🙄 #genetics 🎉
Tamer is the kids version but truthfully I know TONS of adults that use it as well (including yours truly). Just roll it on the stomach and you're good to go! Both Tamer and Digestzen can also be used on the chest and sinus area when you're battling a cold. 😷
Stronger is an immune support similar to yesterdays deal but just a different combo of oils. Also good for kids or adults, it's great to carry with this time of year with all the germs going around!
Plus, this blend has Rose in it which is AMAZING for skin issues, calming and sleep and is great for uplifting your spirits!🤩 🎉
$35 and these three are yours! Reach out by 8pm if you want to order and I can get some for you! These are oils literally EVERYONE needs! #bogoweek#doterra#essentialoils#immunesystem#immunesupport#digestivehealth#digestion#naturalliving#naturalsolutions#nontoxic#makeoveryourmedicinecabinet#kidscollection#kids
1 out of 8 women will face a breast cancer diagnosis, making it one of the deadliest and least understood diseases of our time.
But one doctor has spent 13 years creating a definitive and revolutionary new text on what he believes is primarily an environmental and psychoemotional-triggered illness (fewer than 10% of all cases are linked to genetics). The aim of this groundbreaking reference work, which covers both conventional and complementary treatments, is to allow women to empower themselves - with new thinking and information not readily available elsewhere.
At the 53rd annual Medizinische Woche (“Medicine Week”) in Baden-Baden, Germany, Kelly Kennedy, Executive Director of The True Wellness Center in Pennsylvania, sits down with Dr. James Odell, ND, OMD, L.Ac., one of the world's most esteemed bioregulatory medicine practitioners - and author of Breast Cancer: The Rest of the Story.
Dr. Odell’s encyclopedic 700+-page e-book (and searchable database) is available at https://www.breastcancertherestofthes.... #breastcancer#bioregulatorymedicine#cancer#genetics#epigenetics#hormones#estrogen#breasthealth#breastcancertherestofthestory#family#truewellness#philly#badenbaden#brmi#switzerland#medweek
1 01 hour ago
Nuestro amigo @koala_gakochi_crew sigue sacándole jugo a un clásico de nuestras genéticas, 🔥 #Critical47 🔥toda una campeona que sigue dando resultados indiscutibles y dejando recuerdos por donde es cultivada💚
DNA gathered from remote waterholes in northern Australia has been used to detect an endangered bird in the wild for the first time. The result is the latest milestone in the rapidly maturing science of environmental DNA, in which traces of genetic material from soil, water or ice are used to identify the presence of plants and animals.
In a study published on 14 November in Endangered Species Research, a team in Australia reports that genetic material collected from waterholes showed that Gouldian finches (Erythrura gouldiae) had visited them in the previous 48 hours. Rangers also confirmed the species’ presence at the locations.
Scientists have been using environmental DNA (eDNA) analysis for about 15 years, for purposes including tracking rare or elusive aquatic species, such as the great crested newt (Triturus cristatus) in the United Kingdom. And in the past few years, researchers have increasingly been using the technique to identify mammals, insects — and now birds — that live on land.
Testing for eDNA is often safer — for both animals and researchers — more cost-effective and, in some cases, more accurate and sensitive than conventional methods used to pinpoint rare and endangered species, such as electrofishing surveys or tracking, scientists say. This is prompting regulatory agencies in a number of countries to adopt the technology to locate creatures, such as the endangered Canada lynx (Lynx canadensis) in the United States, or to monitor for invasive species.
#GeneticTesting is the analysis of DNA. Using saliva, blood or tissue, Everything Genetic can see possible gene mutations associated with diseases. They can also predict how your body will respond to drugs and treatments. Visit: everythinggeneticltd.co.uk
We had such a good night on Friday at the Minehead Men’s Hockey Club quiz night, thank you very much for thinking of us.💙 As you can see from the photos, we had a magnificent turn out seeing 22 teams in action.
Well done to all those that won prizes on the night and even if you didn’t, we hope you all had an enjoyable evening.
They raised £602.10, which will be split between Elliot’s Touch and the running of their club.
Thank you very much Dom Bowden for doing such an awesome job at being the quiz master and to everyone that supported us with prizes and your valued time. 💙 @minehead_mens_hockey#quiz#hockey#mitochondrialdisease#cardiology#genetictesting#genetics#elliotstouch#quiznight
0 131 hour ago
Nothing more happier than a *almost* perfect gel 😍👩🏻🔬
The CRISPR gene-editing tool can be used to silence an important hepatitis B virus gene, a proof-of-concept in vitro study suggests.
"It's the first time we've seen CRISPR editing done in a hepatitis B model," said Douglas Dieterich, MD, director of the Institute of Liver Medicine and professor of medicine at the Icahn School of Medicine at Mount Sinai in New York City.
For their study, investigator Hao Zhou, from The First Hospital of Jilin University in China and the Department of Medicine at the University of Minnesota in Minneapolis, and colleagues targeted the S gene.
The S gene gives rise to the hepatitis B surface antigen, the presence of which indicates that a person is infected with the virus. "The question is whether it's the right target," Dieterich told Medscape Medical News.
Reducing the amount of the hepatitis B surface antigen is a "good idea" because that's what is believed to inhibit the immune system from clearing the virus. Doing so might help the immune system recover and clear the virus, "with a little help from some antivirals," explained Dieterich, who was not involved in the study.
However, "the surface is not the only DNA that's integrated into the host genome," he pointed out. "I think maybe a broader application might be necessary to actually get the hepatitis B genome out of the hepatocytes." Zhou's team used a newer CRISPR approach, called CRISPR-STOP, for their gene-editing procedure.
"The idea is that CRISPR-STOP can be as efficient as standard CRISPR editing, but it's safer," said Kiran Musunuru, MD, PhD.
Instead of creating a double-strand break, CRISPR-STOP uses a base editor to chemically modify the DNA base from one base to another and introduce a stop codon into the target gene sequence, effectively hamstringing the ability of the target gene to produce a functional protein.
With the gene-editing approach, 71% of the liver cells that expressed the base editor gained the desired stop codon in the target gene. "That's a very robust number," said Musunuru.
[credit: Christina Bennett, Medscape]🌐
10 1,29616 November, 2019
Throwback Thursday with little Ishy Squishy!!! Have you ever seen something so darn adorbs??? This is little Ishy, our American girl when she was about 6 weeks.... she was given to us and is a good example of nurture vs nature.... she had the very best socialization and training.... she was raised by our Russian foxes, as well.... and in many ways she is a little “Sophie”.... loud, sassy, and loves cucumbers. But genetically she is not a Russian domesticated fox and no matter what we did, we cannot change her DNA!!. When you tame an animal you introduce them to people at a very young age and associate people with positive things. If this is done young enough and intensely enough, some of the natural behaviors towards people can be suppressed but not eliminated. The offspring of these animals would be no more tame than non tamed animals. When you domesticate animals you select against undesirable behaviors towards humans with the intent of eliminating these behaviors. The offspring of these animals would also not possess these undesirable behaviors. Ishy is adorable regardless and part of our pack! .
Using CRISPR-Cas9 technology to reduce the expression of the gene PMP22 in nerve cells can improve nerve functioning and limit demyelination (damage to the protective covering that surrounds nerve fibres) in a mouse model of Charcot-Marie-Tooth disease 1A (CMT1A).
CMT1A, which is the most common type of CMT1, is caused by duplication of a region of human chromosome 17. One of the genes in this region is PMP22 (peripheral myelin protein of 22 kDa), which encodes for a protein of the same name.
It is thought that this duplication leads to too-high levels of PMP22 protein, which in turn helps drive demyelination or the loss of myelin (the protein “sheath” around neurons that helps them function correctly) in CMT1A. Based on this idea, researchers behind this study wanted to develop a method using CRISPR-Cas9 by which they could lower PMP22 expression.
The system was used on one of the sciatic nerves (the nerve that stretches from the hip to the feet) of these mice, with the same nerve on the opposite side of each mouse’s body being used as a control.
The researchers confirmed that nerves targeted in such a way had significantly decreased expression of PMP22 — 44.64% less than controls, on average. Additionally, they found that these nerves had more myelin than untreated nerves, indicating the strategy’s intended effect.
They also tested the system on three-week-old mice. They found that these mice had similar decreased PMP22 expression (by 40.67% on average), and myelin was also increased in treated nerves of these older mice.
Plus, the researchers determined that treated nerves in these mice worked better than untreated ones, as evidenced by increased motor nerve conduction velocity and compound muscle action potential. Basically, the treated nerves were better at signaling electrical signals.
Importantly, the genomes of treated cells were sequenced to look for evidence of off-target effects and the researchers didn’t find any, suggesting that there were none or so few that none were detected.
[credit: Marisa Wexler, Charcot Marie Tooth News]🌐