Pulmonary hypertension is a debilitating
long-term condition characterised by severe
Pulmonary arterial pressure is abnormally raised due to dysfunctional endothelial cells and vascular smooth muscle, leading to maladaptive pulmonary vascular remodelling and increased right ventricular afterload.
Pulmonary and cardiovascular haemodynamics are progressively compromised, often during minimal physical exertion.
Consequently, exertional dyspnoea, fatigue and syncope are the most common symptoms, impacting profoundly on quality of life (QoL), morbidity and mortality.
Guidance from the World Symposium on Pulmonary Hypertension identified 𝐟𝐢𝐯𝐞 𝐝𝐢𝐬𝐭𝐢𝐧𝐜𝐭 𝐬𝐮𝐛𝐠𝐫𝐨𝐮𝐩𝐬:
𝑮𝒓𝒐𝒖𝒑 1—Pulmonary arterial hypertension (PAH) 𝑮𝒓𝒐𝒖𝒑 2—Pulmonary hypertension due to left heart disease
𝑮𝒓𝒐𝒖𝒑 3—Pulmonary hypertension due to lung diseases or hypoxia, or both
𝑮𝒓𝒐𝒖𝒑 4—Chronic thromboembolic pulmo-
nary hypertension (CTEPH)
𝑮𝒓𝒐𝒖𝒑 5—Pulmonary hypertension with unclear
There are many similarities between pulmonary hypertension and conditions like chronic obstructive pulmonary disease and chronic heart failure; indeed, they often coexist.
Exercise therapy improves exercise tolerance and QoL for people living with these conditions; therefore it is plausible that it will also help people living with pulmonary hypertension.
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